1-N-Boc-pyrrolidin-2-ylboronic acid - Names and Identifiers
1-N-Boc-pyrrolidin-2-ylboronic acid - Physico-chemical Properties
Molecular Formula | C9H18BNO4
|
Molar Mass | 215.05 |
Density | 1.15±0.1 g/cm3(Predicted) |
Boling Point | 349.2±52.0 °C(Predicted) |
Flash Point | 165°C |
Solubility | Chloroform (Slightly, Heated), DMSO (Slightly) |
Vapor Presure | 2.89E-06mmHg at 25°C |
Appearance | Solid |
Color | Yellow |
pKa | 9.94±0.20(Predicted) |
Storage Condition | Inert atmosphere,Store in freezer, under -20°C |
Refractive Index | 1.488 |
1-N-Boc-pyrrolidin-2-ylboronic acid - Introduction
acid 1-(1,1-dimethylethyl) ester, also known as TBOA-B, is an organic boron compound. The following is a description of its nature, use, preparation and safety information:
Nature:
The acid 1-(1,1-dimethylethyl) ester is a white solid that is soluble in organic solvents such as methylene chloride and dimethyl sulfoxide. It has good thermal stability and solubility, and can be applied under a wide range of temperature and solvent conditions.
Use:
acid 1-(1,1-dimethylethyl) ester is widely used in organic synthetic chemistry. It can be used as a carboxylic acid protector and stabilizer for reference compounds in organic synthesis reactions. In addition, it can also be used as a catalyst precursor to participate in the catalytic process of organic synthesis reactions. Other applications include drug research, ligand design, and catalytic reaction mechanism research.
Method:
acid 1-(1,1-dimethylethyl) ester is usually synthesized by chemical synthesis methods. One of the commonly used methods is the reaction of a pyrrolidine-2-iodo compound with N-tert-butoxycarbonyl-1, 1 '-dicyclopropylthiourea borate to produce the final product.
Safety Information:
regarding the safety information of acid 1-(1,1-dimethylethyl) ester, no particularly dangerous nature has been found so far, but it is still necessary to pay attention to safe operation. Inhalation of its dust or solution should be avoided, and it should be rinsed immediately with plenty of water when in contact with skin and eyes. During use and storage, the general safety instructions for chemicals should be followed, the operating environment should be well ventilated, and appropriate protective equipment and gloves should be worn. If necessary, the relevant regulations and guidelines for chemicals should be followed.
Last Update:2024-04-09 20:52:54